one. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity connected to bortezomib, a proteasome inhibitor Utilized in the treatment of a number of myeloma. Its synthesis or examine is essential for ensuring the purity and protection with the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor within the synthesis of abiraterone acetate, a drug used in the cure of prostate cancer by inhibiting androgen production.
Imatinib Intermediate (CAS NO. 152460-10-one): A essential compound inside the synthesis of imatinib, a drug that targets unique sorts of cancer, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers for instance breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They're intermediates within the synthesis of gemcitabine, an anti-cancer drug. Their analyze is significant for optimizing the production approach and making sure large purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): CAS NO. 314771-76-1 Lapatinib is used to deal with breast most cancers, and these intermediates are involved in its creation.
Fulvestrant Intermediates: Fulvestrant is an estrogen receptor antagonist used in the treatment method of breast most cancers. Various intermediates help in the synthesis of the drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-sixteen-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in dealing with cancers which include ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the cure of colorectal most cancers and compact mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is linked to the synthesis of adamantane derivatives, that have many applications, such as antiviral Qualities.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for sort 2 diabetes that inhibits the enzyme DPP-4 to control blood sugar degrees.
4. Miscellaneous Compounds
D-Gluconic Acid Imatinib Impurity C δ-Lactone (CAS NO. 61259-forty eight-1): This compound is involved with the synthesis of various gluconic acid derivatives, which might be used in food stuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate two: A precursor while in the synthesis of canagliflozin, a medication employed to deal with variety two diabetes by inhibiting sodium-glucose co-transporter two (SGLT2).